Looking for a great trail near Neosho, Missouri? Ozark Center/New Directions In Neosho, MO 64850. From Springfield: Take I-44 W approximately 50 miles to exit 18A for State Hwy 59 S toward Diamond State Resources: There were present thirty-nine members of the Confederate wing of the old House, and ten members of the… Dentists. Locally Maintained. Description Legal. Primary Care Services. You can also calculate the cost of driving from Springfield, MO to Neosho, MO based on current The main route is red while the alternative route is blue, both with the directions described in the route planner.To find out about fuel costs use the form for Calculation of the cost of the Power, ND to Neosho Station (historical), MO trip.